产品详情 |
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Product Name | Δ4-Abiraterone |
Description | An active metabolite of abiraterone; androgen receptor antagonist (IC50 = 5.3 nM); reduces expression of androgen receptor target genes in LNCaP, LAPC4, and C4-2 cell lines; inhibits CYP17A1 at 1 nM; blocks SRD5A conversion of Δ4-androstenedione to 5α-androstanedione in LAPC4 cells at 10 µM; delays tumor progression in a VCaP mouse xenograft model; increases progression-free survival in a C4-2 mouse xenograft model |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | CB 7627|D4A |
Gene, Accession, CAS # | CAS: 154229-21-7 |
Catalog # | 27594-5 |
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Order / More Info | Δ4-Abiraterone from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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