| 产品详情 |
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| Product Name | Regorafenib |
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| Description | A multi-kinase inhibitor; inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ (IC50s = 1.5, 2.5, 4.2, 7, 13, and 22 nM, respectively); inhibits B-RAF, VEGFR3, FGFR, and Tie2 (IC50s = 28, 46, 202, and 311 nM, respectively); reduces tumor size in the MDA-MB-231 breast and 786-O renal cancer mouse xenograft models at 10 mg/kg; reduces tumor microvessel area and inhibits tumor growth in a panel of mouse xenograft models |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | BAY 73-4506 |
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| Gene, Accession, CAS # | CAS: 755037-03-7 |
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| Catalog # | 18498-10 |
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| Price | |
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| Order / More Info | Regorafenib from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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