| 产品详情 |
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| Product Name | C527 |
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| Description | An inhibitor of the USP1/UAF complex; inhibits USP1/UAF deubiquitinase activity (IC50 = 0.88 µM); inhibits USP5, UCL-H3, and USP12/46 but not UCL-H1 activity (IC50s = 1.65, 2.18, 5.97, and >10 µM, respectively); inhibits homologous recombination repair, cell proliferation, and sensitizes HeLa cells to the DNA crosslinker mitomycin C; inhibits proliferation of PC3 and LNCap prostate cancer cells (IC50s = 0.24 and 0.03 µM, respectively, after 72 hours) |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | C-527 USP-5 UCLH3 1 USP-12/46 PC-3 D-2 |
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| Gene, Accession, CAS # | CAS: 192718-06-2 |
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| Catalog # | 21771-25 |
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| Price | |
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| Order / More Info | C527 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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