| 产品详情 |
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| Antigenic Specificity | MCPT-1 (mMCP-1) |
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| Clone | RF6.1 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | ELISA: Assay-Dependent, Immunocytochemistry: Assay-Dependent, Immunofluorescence: Assay-Dependent, Immunohistochemistry: Assay-Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MCPT-1 (mMCP-1) Monoclonal Antibody (RF6.1), eBioscience™. MCPT-1 is the only chymase expressed by intestinal mucosal mast cells, which are found in the intestinal epithelium. Although it is expressed constitutively and is detectable in the sera of normal mice, parasites in the gut cause systemic levels to increase dramatically within two days and peak at two weeks following infection. It plays an important role in host defense against intestinal parasites, as mice deficient in MCPT-1 display delayed response upon infection. Elevated MCPT-1 levels are also observed during intestinal allergic hypersensitivity reactions. The mechanism of its action is not fully understood, although it is believed to increase intestinal permeability simi |
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| Immunogen | n/a |
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| Other Names | n/a |
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| Gene, Accession # | Entrez: 17224; Uniprot: P11034 |
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| Catalog # | 14-5503-82 |
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| Price | |
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| Order / More Info | MCPT-1 (mMCP-1) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 25517090 |
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