产品名称 PF 5274857 hydrochloride from TOCRIS BIOSCIENCE
产品货号 5262/50
产品价格 现货询价,电话:010-67529703
产品规格 50 mg
产品品牌 TOCRIS BIOSCIENCE
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Product NamePF 5274857 hydrochloride
DescriptionHigh affinity and selective Smoothened (Smo) receptor antagonist (Ki = 4.6 nM). Exhibits >1000-fold selectivity for Smo over a panel of other receptors, ion channels and enzymes. Inhibits Shh-induced Hedgehog signaling in MEF cells. Induces tumor regression in a medulloblastoma allograft mouse model. Orally available and brain penetrant. Purity 98%. MW (observed): 473.42
Size50 mg
Concentrationn/a
Applicationsn/a
Other Names1-[4-(5'-Chloro-3,5-dimethyl[2,4'-bipyridin]-2'-yl-1-piperazinyl]-3-(methylsulfonyl)-1-propanone hydrochloride
Gene, Accession, CAS #CAS: 1613439-62-5
Catalog #5262/50
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Order / More InfoPF 5274857 hydrochloride from TOCRIS BIOSCIENCE
Product Specific Referencesn/a
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