| 产品详情 |
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| Product Name | AZD 2858 |
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| Description | A GSK3β inhibitor (Ki = 4.9 nM) that crosses the blood brain barrier and inhibits tau phosphorylation (IC50 = 76 nM in vitro); stabilizes β-catenin and increases bone mass (via Wnt activation) in rats after a two-week treatment with a maximum effective oral dose of 20 mg/kg once daily |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 486424-21-9 GSK3β inhibitor anabolic glycogen synthase kinase-3β osteogenesis Alzheimer's disease tau phosphorylating bone formation mineralization Wnt β-catenin stem cell related research inhibit biochemical GSK3β phosphorylate protein AZD2858 pyrazine analog blood brain barrier phosphorylation in vitro mass activation rats mesenchymal osteoblast differentiation |
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| Gene, Accession, CAS # | CAS: 486424-20-8 |
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| Catalog # | 16728-10 |
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| Order / More Info | AZD 2858 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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