| 产品详情 |
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| Product Name | AZD 1080 |
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| Description | A potent, selective, brain permeable inhibitor of GSK3α and GSK3β (Kis = 6.9 and 31 nM, respectively); shows good bioavailability after oral administration in vivo, inhibiting hippocampal tau phosphorylation and reversing cognitive deficits induced by the NMDA receptor antagonist (+)-MK-801 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | biochemical inhibitor kinase protein Alzheimer's research bone-related research neuroscience glycogen synthase kinase-3α kinase-3β GSK3α GSK3β GSK-3α GSK-3β isoform phosphorylate phosphorylation inactivate inactivation synthesis disease osteogenesis AZD1080 brain permeable receptor enzyme ion channel tau cell oral administration in vivo hippocampal hippocampus cognitive deficit NMDA antagonist MK-801 MK801 human peripheral blood lymphocyte |
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| Gene, Accession, CAS # | CAS: 612487-72-6 |
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| Catalog # | 16676-10 |
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| Price | |
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| Order / More Info | AZD 1080 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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