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Antigenic Specificity | CD11a (LFA-1alpha) |
Clone | R7.1 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | biotin conjugate |
Size | 100 Tests |
Concentration | n/a |
Applications | Flow Cytometry: Assay-Dependent, Functional Assay: Assay-Dependent, Immunohistochemistry: Assay-Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD11a (LFA-1alpha) Monoclonal Antibody (R7.1), Biotin, eBioscience™. CD11a (LFA-1 alpha, ITGAL) together with CD18 constitute leukocyte function-associated antigen 1 (LFA-1), the alphaLbeta2 integrin. CD11a is implicated in activation of LFA-1 complex. CD11a plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. CD11a is expressed on the plasma membrane of leukocytes in a low-affinity conformation. Cell stimulation by chemokines or other signals leads to induction the high-affinity conformation, which supports tight binding of CD11a to its ligands, the intercellular adhesion molec |
Immunogen | n/a |
Other Names | CD11 antigen-like family member A, LFA-1 alpha, LFA-1A, antigen CD11A p180, lymphocyte function-associated antigen 1 alpha polypeptide, integrin alpha-L |
Gene, Accession # | Entrez: 3683; Uniprot: P20701 |
Catalog # | BMS102BT |
Price | |
Order / More Info | CD11a (LFA-1alpha) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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