| 产品详情 |
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| Antigenic Specificity | CD11a (LFA-1alpha) |
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| Clone | I21/7 |
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| Host Species | Rat |
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| Reactive Species | human, mouse |
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| Isotype | IgG2a |
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| Format | phycoerythrin (PE) conjugate |
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| Size | 1 mL |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 0.2 µg/10^6 cells |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD11a (LFA-1alpha) Monoclonal Antibody (I21/7), PE. CD11a (LFA-1 alpha, ITGAL) together with CD18 constitute leukocyte function-associated antigen 1 (LFA-1), the alphaLbeta2 integrin. CD11a is implicated in activation of LFA-1 complex. CD11a plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. CD11a is expressed on the plasma membrane of leukocytes in a low-affinity conformation. Cell stimulation by chemokines or other signals leads to induction the high-affinity conformation, which supports tight binding of CD11a to its ligands, the intercellular adhesion molecules ICAM-1, -2, -3. CD |
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| Immunogen | n/a |
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| Other Names | LFA-1, LFA-1 alpha, integrin alphaL |
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| Gene, Accession # | Entrez: 16408, 3683; Uniprot: P20701, P24063 |
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| Catalog # | MA5-28641 |
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| Price | |
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| Order / More Info | CD11a (LFA-1alpha) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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