| 产品详情 |
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| Product Name | PHT-427 |
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| Description | An inhibitor of Akt and PDPK1 (Ki = 2.7 and 5.2 µM, respectively); binds to the pleckstrin homology binding domain; inhibits PDPK1 and Akt autophosphorylation in BxPC-3 prostate cancer cells (10 µM); reduces tumor growth in BxPC-3, Panc-1, MiaPaCa-2, PC3, SK-OV-3, A549, and MCF-7 xenograft mouse models (125-250 mg/kg); enhances the antitumor effect of paclitaxel in an MCF-7 breast cancer xenograft mouse model, |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Akt Inhibitor XIV |
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| Gene, Accession, CAS # | CAS: 1191951-57-1 |
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| Catalog # | 24188-50 |
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| Price | |
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| Order / More Info | PHT-427 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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