| 产品详情 |
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| Antigenic Specificity | SLA |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SLA Polyclonal Antibody. SLAP also known as Src-like-adapter protein 1 is a 276 amino acid containing adapter protein, functioning as a negative regulator of T-cell receptor (TCR) signaling. SLAP belonging to the SRC family of cytoplasmic tyrosine kinases contains a SH2 domain and a SH3 domain. This cytoplasmic protein colocalizes with endosomes and is known to inhibit T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. It acts as a negative regulator of positive selection and mitosis of T-cells. SLAP may act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins. Expression of SLAP is weak in heart, adult brain, placenta, liver, skeletal muscle, kidn |
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| Immunogen | n/a |
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| Other Names | SLA1; SLAP; SLAP-1; hSLAP; src-like-adapter; src-like-adapter protein 1 |
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| Gene, Accession # | Entrez: 6503; Uniprot: Q13239 |
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| Catalog # | PA5-67335 |
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| Price | |
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| Order / More Info | SLA Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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