产品详情 |
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Antigenic Specificity | HAI-2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunohistochemistry: 1:200-1:500, Western Blot: 0.4 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | HAI-2 Polyclonal Antibody. HAI-2 is an endogenous inhibitor of the kunitz-type serine proteinase HGF-activator (HGFA). HGF was first described as a hepatocyte-specific mitogen and survival factor, and has since been shown to exert a variety of actions on many cell types by binding to its MET receptor. HGF is activated by cleavage of the single-chain form to form a two-chain version by HGFA. HAI-2 also inhibits trypsin, and MTSP-1 (Matriptase-1), a serine proteinase that also activates HGF, and HGF-2 has been shown to inhibit hepsin with nanamolar kIs. HAI-2 was first known as bikunin, and SPINT2 (Serine Proteinase Inhibitor-2), a proteinase inhibitor found in amniotic fluid. A protein termed HAI-2 related small protein is a 106 amino acid p |
Immunogen | n/a |
Other Names | SPINT2; serine peptidase inhibitor, Kunitz type, 2; DIAR3; FLJ45571; HAI-2; HAI2; Kop; PB; hepatocyte growth factor activator inhibitor type 2; placental bikunin; serine protease inhibitor, Kunitz type, 2 |
Gene, Accession # | Entrez: 10653; Uniprot: O43291 |
Catalog # | PA5-52790 |
Price | |
Order / More Info | HAI-2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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