| 产品详情 |
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| Antigenic Specificity | CD283 (TLR3) |
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| Clone | 11F8 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a |
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| Format | fluorescein (FITC) conjugate |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: Assay-dependent, Immunofluorescence: Assay-dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD283 (TLR3) Monoclonal Antibody (11F8), FITC. TLR3 is involved in Herpes simplex encephalitis 2 (HSE2), a rare complication of human herpesvirus 1 (HHV-1) infection, occurring in only a small minority of HHV-1 infected individuals. HSE is characterized by hemorrhagic necrosis of parts of the temporal and frontal lobes. Onset is over several days and involves fever, headache, seizures, stupor, and often coma, frequently with a fatal outcome. Disease susceptibility is associated with variations affecting the gene represented in this entry. TLR3 mutations predispose otherwise healthy individuals to isolated herpes simplex encephalitis through a mechanism that involves impaired IFNs production and reduced immune defense against viral infection |
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| Immunogen | n/a |
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| Other Names | n/a |
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| Gene, Accession # | Entrez: 142980; Uniprot: Q99MB1 |
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| Catalog # | MA5-28249 |
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| Price | |
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| Order / More Info | CD283 (TLR3) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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