| 产品详情 |
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| Antigenic Specificity | VHL |
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| Clone | polyclonal |
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| Host Species | Goat |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | ELISA: 1.5-3.0 µg/mL, Immunohistochemistry: 5 µg/mL, peptide-ELISA: 1:128000, Western Blot: 0.01-0.03 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | VHL Polyclonal Antibody. Von Hippel-Lindau syndrome is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of this gene is the basis of familial inheritance of VHL syndrome. The protein encoded by this gene is a component of the protein complex that includes elongin B, elongin C, and cullin-2, and possesses ubiquitin ligase E3 activity. This protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor , which is a transcription factor that plays a central role in the regulation of gene expression by oxygen. RNA polymerase II subunit POLR2G/RPB7 is also reported to be a target of this protein. Alternatively spliced transcript variants encoding |
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| Immunogen | n/a |
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| Other Names | VHL; von Hippel-Lindau tumor suppressor; HRCA1; RCA1; VHL1 ; elongin binding protein; von Hippel-Lindau syndrome |
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| Gene, Accession # | Entrez: 22346, 24874, 7428; Uniprot: P40337, P40338, Q64259 |
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| Catalog # | PA5-18549 |
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| Price | |
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| Order / More Info | VHL Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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