产品详情 |
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Antigenic Specificity | VEGF Receptor 2 |
Clone | 4B4 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Flow Cytometry: 1/200 - 1/400, Immunocytochemistry: 1:200-1:1000, Immunofluorescence: 1/200 - 1/1000, Western Blot: 1/500 - 1/2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | VEGF Receptor 2 Monoclonal Antibody (4B4). Vascular endothelial growth factor is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc. Mutations of this gene are implicated in infantile capillary hemangiomas. |
Immunogen | n/a |
Other Names | 6130401C07, Flk-1, Flk1, Krd-1, Ly73, VEGFR-2, VEGFR2, sVEGFR-2, CD309, KDR |
Gene, Accession # | Entrez: 3791; Uniprot: P35968 |
Catalog # | MA5-15556 |
Price | |
Order / More Info | VEGF Receptor 2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 27942994 |
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