| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | PPM1D |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human, mouse, rat |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 100 µl |
|---|
| Concentration | n/a |
|---|
| Applications | Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:2000 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | PPM1D Polyclonal Antibody. Several major serine/threonine protein phosphatases have been identified in eukaryotic cells. These include protein phosphatase families 1, 2A, 2B, 2C, X and Y (PP-1, PP-2A, PP-2B, PP-2C, PP-X and PP-Y). These enzymes can be distinguished by their action on phosphorylase kinase and their sensitivity to certain activators and inhibitors. Wip1 (wildtype p53-induced phosphatase or PPM1D), a protein identified in the p53 DNA response pathway, is a member of the PP-2C family. Wip1 is a serine/threonine protein phosphatase which selectively inactivates p38 MAPK and dephosphorylates the ATM/ATR targets, Chk1 and p53. Wip1 is ubiquitously expressed but is present at very high levels in testis. Deletion of Wip1 results in |
|---|
| Immunogen | n/a |
|---|
| Other Names | p53 induced protein phosphatase 1;p53-induced protein phosphatase 1;PP2C delta;PP2C-delta;PP2CD;Ppm1d;PPM1D_HUMAN;Protein phosphatase 1D;protein phosphatase 1D magnesium-dependent delta isoform;Protein phosphatase 2C delta isoform;Protein phosphatase 2C isoform delta;Protein phosphatase magnesium dependent 1 delta;Protein phosphatase magnesium-dependent 1 delta;WIP 1;WIP1; |
|---|
| Gene, Accession # | Entrez: 287585, 53892, 8493; Uniprot: O15297, Q9QZ67 |
|---|
| Catalog # | PA5-76866 |
|---|
| Price | |
|---|
| Order / More Info | PPM1D Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|