| 产品详情 |
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| Antigenic Specificity | PPL |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: 1:500-1:3000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PPL Polyclonal Antibody. The protein encoded by this gene is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling. |
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| Immunogen | n/a |
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| Other Names | 190 kDa paraneoplastic pemphigus antigen, 195 kDa cornified envelope precursor protein |
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| Gene, Accession # | Entrez: 19041, 5493; Uniprot: O60437, Q9R269 |
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| Catalog # | PA5-30931 |
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| Price | |
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| Order / More Info | PPL Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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