产品详情 |
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Antigenic Specificity | CLCN4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunocytochemistry: 1:50-1:200, Immunofluorescence: 1:50-1:200, Western Blot: 1:500-1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CLCN4 Polyclonal Antibody. The family of voltage-dependent chloride channels (CLCs) regulate cellular trafficking of chloride ions, a critical component of all living cells. CLCs regulate excitability in muscle and nerve cells, aid in organic solute transport and maintain cellular volume. The genes encoding human CLC-1 through CLC-7 map to chromosomes 7, 3q26, 4q32, Xp22, Xp11, 1p36 and 16p13, respectively. CLC-1 is highly expressed in skeletal muscle. Mutations in the gene encoding CLC-1 lead to myotonia, an inheritable disorder characterized by muscle stiffness and renal salt wasting. CLC-2 is highly expressed in the epithelia of several organs including lung, which suggests CLC-2 may be a possible therapeutic target for cystic fibrosis. |
Immunogen | n/a |
Other Names | H(+)/Cl(-) exchange transporter 4; Chloride channel protein 4; ClC-4; Chloride transporter ClC-4; CLCN4; CLC 4; CLC4 |
Gene, Accession # | Entrez: 1183, 12727, 60586; Uniprot: P51793, P51794, Q61418 |
Catalog # | PA5-75392 |
Price | |
Order / More Info | CLCN4 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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