| 产品详情 |
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| Antigenic Specificity | ERAS |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:100 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ERAS Polyclonal Antibody. The human ERAS gene was initially reported as a processed pseudogene (HRasp, Ha-Ras2), with several base substitutions in coding regions, but was more recently described as potentially encoding a functional human ERAS protein. The ERAS oncogene supports the tumorigenic growth of embryonic stem cells by producing a constitutively active Ras protein. ERAS protein has less than 50% amino acid identity with H-Ras, another member of Ras family but the key domains essential for Ras function are highly conserved. The protein also contains amino-acid residues identical to those present in active mutants of Ras and causes oncogenic transformation in NIH 3T3 cells. Human ERAS gene is localized in the chromosomal region Xp11. |
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| Immunogen | n/a |
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| Other Names | HRAS2, HRASP, E-Ras, GTPase ERas, embryonic stem cell-expressed Ras, small GTPase protein E-Ras, v-Ha-ras Harvey rat sarcoma viral oncogene homolog 2, v-Ha-ras Harvey rat sarcoma viral oncogene homolog pseudogene |
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| Gene, Accession # | Entrez: 3266, 679682; Uniprot: Q7Z444 |
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| Catalog # | PA5-23240 |
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| Price | |
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| Order / More Info | ERAS Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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