| 产品详情 |
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| Antigenic Specificity | IFNAR1 |
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| Clone | MAR1-5A3 |
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| Host Species | Mouse |
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| Reactive Species | mouse |
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| Isotype | IgG1, kappa |
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| Format | unconjugated, functional grade |
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| Size | 500 µg |
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| Concentration | n/a |
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| Applications | Functional Assay: Assay-Dependent, Neutralization: Assay-Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | IFNAR1 Monoclonal Antibody (MAR1-5A3), Functional Grade, eBioscience™. Interferons are widely used therapeutic agents because of their anti tumor and antiviral effects and because of their modulatory effects on the immune system (Biron,2001, Kirkwood, 2002). These cytokines produce their effects by binding to the Type 1 Interferon-& Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is thought to be influenced by phosphorylation of Serine 535 and 539 in the IFNAR1 (Kumar et al., 2003). |
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| Immunogen | n/a |
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| Other Names | n/a |
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| Gene, Accession # | Entrez: 15975; Uniprot: P33896 |
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| Catalog # | 16-5945-85 |
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| Price | |
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| Order / More Info | IFNAR1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 21068399, 24145513, 24711619, 24713170, 26392465, 27075414, 27776548, 28069953 |
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