| 产品详情 |
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| Antigenic Specificity | E2F1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 50 µl, 100 µl, 200 µl |
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| Concentration | > 1 mg/ml |
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| Applications | WB. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | E2F1 Antibody is a Rabbit Polyclonal antibody against E2F1. The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis. |
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| Immunogen | A synthetic peptide of human E2F1. |
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| Other Names | E2f; E2F transcription factor; Dmel_CG6376; CG6376; DRTF1/E2F; DmE2F-1; Dmel\CG6376; Dp; E(Sev-CycE)3A; E(var)3-93E; E(var)3-95E; E(var)93E; E2F-1; E2F1; Evar(3)164; dE2F; dE2F1; def21; drosE2F1; l(3)07172; l(3)j3; e2f1; PBR3; PRB-binding protein E2F-1; RBAP-1; RBBP-3; RBBP3; Retinoblastoma binding protein 3; Retinoblastoma-associated protein 1; Transcription factor E2F1; RBAP1; RBP3; Retinoblastoma-binding protein 3; Transcription factor E2F1E2F-1 |
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| Gene, Accession # | E2F1, Gene ID: 1869, SwissProt: Q01094 |
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| Catalog # | abx001684 |
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| Price | |
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| Order / More Info | E2F1 Antibody from ABBEXA |
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| Product Specific References | n/a |
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