| 产品详情 |
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| Antigenic Specificity | E2F1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | peptide affinity purified |
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| Size | 80 µl, 400 µl |
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| Concentration | n/a |
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| Applications | WB. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | E2F1 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another two members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis. This E2F1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 310-344 amino acids from human E2F1. |
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| Immunogen | Human E2F1. |
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| Other Names | E2f; E2F transcription factor; Dmel_CG6376; CG6376; DRTF1/E2F; DmE2F-1; Dmel\CG6376; Dp; E(Sev-CycE)3A; E(var)3-93E; E(var)3-95E; E(var)93E; E2F-1; E2F1; Evar(3)164; dE2F; dE2F1; def21; drosE2F1; l(3)07172; l(3)j3; e2f1; PBR3; PRB-binding protein E2F-1; RBAP-1; RBBP-3; RBBP3; Retinoblastoma binding protein 3; Retinoblastoma-associated protein 1; Transcription factor E2F1; RBAP1; RBP3; Retinoblastoma-binding protein 3; Transcription factor E2F1E2F-1 |
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| Gene, Accession # | SwissProt: Q01094 |
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| Catalog # | abx033498 |
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| Price | |
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| Order / More Info | E2F1 Antibody from ABBEXA |
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| Product Specific References | n/a |
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