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| Antigenic Specificity | PYCARD |
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| Clone | polyclonal |
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| Host Species | Goat |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 2-4 µg/mL, Immunohistochemistry: 2.5 µg/mL, peptide-ELISA: 1:32000, Western Blot: 1-3 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PYCARD Polyclonal Antibody. This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. |
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| Immunogen | n/a |
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| Other Names | PYCARD; PYD and CARD domain containing; ASC; CARD5; MGC10332; TMS1; apoptosis-associated speck-like protein containing a CARD; caspase recruitment dom |
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| Gene, Accession # | Entrez: 29108; Uniprot: Q9ULZ3 |
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| Catalog # | PA1-9010 |
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| Price | |
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| Order / More Info | PYCARD Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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