| 产品详情 |
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| Product Name | TPCA-1 |
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| Description | Potent, selective inhibitor of IκB kinase (IKK) β (IC50 = 17.9 nM) that displays > 22-fold selectivity over IKKα and > 550-fold selectivity over other kinases and enzymes. Inhibits production of pro-inflammatory cytokines in vitro and in vivo and inhibits NF-κB nuclear localization. Reduces the severity and onset of collagen-induced arthritis; anti-inflammatory. Purity 97%. MW (observed): 279.29 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-[(Aminocarbonyl)amino]-5-(4-fluorophenyl)-3-thiophenecarboxamide |
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| Gene, Accession, CAS # | CAS: 507475-17-4 |
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| Catalog # | 2559/10 |
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| Price | |
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| Order / More Info | TPCA-1 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 21850048, 24489934, 24570002, 25803615, 26331681, 27549131, 27560715, 28378740 |
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