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| Product Name | Topotecan hydrochloride |
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| Description | DNA topoisomerase I inhibitor; induces rapid apoptotic death in human B-lineage acute lymphoblastic leukemia (ALL) cells. Improves survival in three mouse models of poor prognosis ALL; downregulates B-Myb and MycN expression in neuroblastoma cells. Water-soluble analog of Camptothecin (Cat. No. 1100). Orally bioavailable. Purity 98%. MW (observed): 457.91 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione hydrochloride. SK&F 104864-A |
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| Gene, Accession, CAS # | CAS: 119413-54-6 |
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| Catalog # | 4562/50 |
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| Order / More Info | Topotecan hydrochloride from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 27029645 |
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