产品详情 |
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Product Name | Toceranib |
Description | Potent ATP-competitive PDGFR and VEGFR inhibitor (Ki = 5 and 6 nM, respectively); inhibits phosphorylation of c-Kit and suppresses the growth of mast cell lines expressing mutant Kit, inducing cell cycle arrest and apoptosis. Also inhibits FGFR1 (Ki = 0.5 μM). Effective in vivo. Purity 98%. MW (observed): 396.46 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 5-[(Z)-(5-Fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-N-[2-(1-pyrrolidinyl)ethyl]-1H-pyrrole-3-carboxamide. Palladia |
Gene, Accession, CAS # | CAS: 356068-94-5 |
Catalog # | 3909/50 |
Price | |
Order / More Info | Toceranib from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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