| 产品详情 |
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| Product Name | LDN 212854 |
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| Description | Potent ALK inhibitor (IC50 values are 1.3, 2.4, 85.8, 2,133 and 9,276 nM for ALK2, ALK1, ALK3, ALK4 and ALK5, respectively). Exhibits selectivity for ALK2 over ALK4 and ALK5 in cellular assays. Inhibits heterotopic ossification in a mutant ALK2 mouse model of fibrodysplasia ossificans progressiva. Also exhibits activity against RIPK2, ABL1 and PDGFR-β (IC50 values < 100 nM). Purity 98%. MW (observed): 406.48 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 5-(6-(4-(1-Piperazinyl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline |
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| Gene, Accession, CAS # | CAS: 1432597-26-6 |
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| Catalog # | 6151/10 |
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| Price | |
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| Order / More Info | LDN 212854 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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| 产品资料 |
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