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Product Name | LDC 000067 |
Description | Potent and selective CDK9 inhibitor (IC50 = 44 nM at CDK9-cyclin T1). Inhibits other CDKs in the micromolar range (IC50 values are 2.4, 5.5, 9.2, >10 and >10 μM for CDK2-cyclin A, CDK1-cyclin B1, CDK4-cyclin D1, CDK6-cyclin D3 and CDK7-cyclin H-MAT1, respectively). Inhibits P-TEFb-dependent in vitro transcription. Induces apoptosis in vitro and in vivo in combination with BI 894999. Purity 98%. MW (observed): 370.43 |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 3-[[6-(2-Methoxyphenyl)-4-pyrimidinyl]amino]benzenemethanesulfonamide |
Gene, Accession, CAS # | CAS: 1073485-20-7 |
Catalog # | 6752/5 |
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Order / More Info | LDC 000067 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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