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| Product Name | Lapatinib |
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| Description | Potent and selective dual ErbB2 (HER-2) and EGFR inhibitor (IC50 values are 9.8 and 10.2 nM, respectively). Selective for EGFR and ErbB-2 versus other proliferative kinases. Inhibits proliferation in multiple cancer cell lines (average IC50 values <0.16 μM). Exhibits 100-fold average selectivity for the tumor cells versus human foreskin fibroblasts. Inhibits EGFR/ErbB2 autophosphorylation and phosphorylation of the downstream modulator AKT. Purity 98%. MW (observed): 581.06 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine |
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| Gene, Accession, CAS # | CAS: 231277-92-2 |
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| Catalog # | 6811/10 |
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| Price | |
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| Order / More Info | Lapatinib from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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| 产品资料 |
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