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| Product Name | SC 144 hydrochloride |
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| Description | Inhibitor of gp130 (IC50 = 0.72 μM); blocks cytokine-triggered gp130 signaling. Induces gp130 phosphorylation and down regulates gp130 glycosylation; also abrogates STAT3 phosphorylation, nuclear translocation and inhibits the expression of downstream target genes. Delays tumor growth in a mouse xenograft model of human ovarian cancer. Orally active. Purity 98%. MW (observed): 358.76 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-(7-Fluoropyrrolo[1,2-a]quinoxalin-4-yl) 2-pyrazinecarboxylic acid hydrazide hydrochloride |
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| Gene, Accession, CAS # | CAS: 917497-70-2 |
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| Catalog # | 4963/10 |
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| Price | |
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| Order / More Info | SC 144 hydrochloride from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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