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Product Name | Narciclasine |
Description | Exhibits antiproliferative and pro-apoptotic effects in carcinoma cells and displays cytotoxic activity against a panel of 60 cancer cell lines (mean IC50 = 47 nM). Activity decreases rate of cell division and increases mitosis duration in vitro. Also modulates the Rho/ROCK/LIM kinase/cofilin pathway; stimulates RhoA activation and induces actin polymerization. Purity 98%. MW (observed): 307.26 |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | (2S,3R,4S,4aR)-3,4,4a,5-Tetrahydro-2,3,4,7-tetrahydroxy-(1,3)dioxolo(4,5-j)phenanthridin-6(2H)-one |
Gene, Accession, CAS # | CAS: 29477-83-6 |
Catalog # | 3715/1 |
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Order / More Info | Narciclasine from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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