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Product Name | GNE 9278 |
Description | Positive allosteric modulator of NMDA receptors. Potentiates NMDA receptors containing GluN2A, 2B, 2C and 2D subunits (EC50 values are 0.74, 3.07, 0.47 and 0.32 μM in a Ca2+ influx assay, respectively). Binds within the transmembrane domain and displays preference for agonist-bound NMDA receptors. Slows receptor deactivation and enhances the potency of glutamate and glycine. Purity 98%. MW (observed): 429.54 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 4-Cyclohexyl-N-(7-hydroxy-5-methyl-2-propyl[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)benzenesulfonamide |
Gene, Accession, CAS # | CAS: 901230-11-3 |
Catalog # | 6369/10 |
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Order / More Info | GNE 9278 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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