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Product Name | Glibenclamide |
Description | ATP-dependent K+ channel (Kir6, KATP) and CFTR Cl- channel blocker. Inhibits Kir6 currents in the pancreas, causing an increase in intracellular Ca2+ and insulin secretion. Inhibits recombinant CFTR Cl- channels with an IC50 of 20 μM. Purity 99%. MW (observed): 494 |
Size | 100 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 5-Chloro-N-[2-[4-[[[(Cylcohexylamino)carbonyl]amino]sulphonyl]phenyl]ethyl]-2-methoxybenzamide. Glyburide |
Gene, Accession, CAS # | CAS: 10238-21-8 |
Catalog # | 0911/100 |
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Order / More Info | Glibenclamide from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 18625211, 20191036, 20393140, 20554857, 20977894, 21664434, 21844078, 21900507, 23082064, 23799098, 24454277, 24800210, 25803863, 25886126 |
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