产品详情 |
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Product Name | ER 819762 |
Description | Potent EP4 receptor antagonist (IC50 = 59 nM). Suppresses EP4-mediated Th1 differentiation, Th17 cell expansion, and IL-23 secretion by activated dendritic cells. Inhibits Th1 and Th17 cytokine production, suppresses collagen- and GPI-induced arthritis in mice. Attenuates CFA-induced inflammatory pain in rats. Analgesic. Orally bioavailable. Purity 98%. MW (observed): 489.65 |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | (10S)-1'-[(3,5-Dimethylphenyl)methyl]-2-ethyl-5,10-dihydro-7,9-dimethoxy-10-methylspiro[1H-imidazo[1,5-b][2]benzazepine-1,4'-piperidin]-3(2H)-one |
Gene, Accession, CAS # | CAS: 1155773-15-1 |
Catalog # | 5924/5 |
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Order / More Info | ER 819762 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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