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| Product Name | Wnt-C59 |
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| Description | Highly potent inhibitor of Porcupine (PORCN), a membrane-bound O-acyltransferase (MBOAT) (IC50 = 74 pM). Shown to inhibit Wnt signaling pathways. Blocks progression of mammary tumors in MMTV-WNT1 transgenic mice and downregulates Wnt/β-catenin target genes. Induces cardiomyocyte differentiation from human iPSCs following culture with CHIR 99021 (Cat. No. 4423). Cell permeable and orally bioavailable. Purity 99%. MW (observed): 379.45 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-(2-Methyl-4-pyridinyl)-N-[4-(3-pyridinyl)phenyl]benzeneacetamide |
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| Gene, Accession, CAS # | CAS: 1243243-89-1 |
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| Catalog # | 5148/50 |
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| Order / More Info | Wnt-C59 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 28077488, 28523267, 28729840, 28959214 |
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