产品详情 |
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Product Name | WM 1119 |
Description | High affinity and competitive lysine acetyltransferase 6A (KAT6A/MOZ) inhibitor (Kd = 2 nM). Displays >250-fold affinity for KAT6A compared to KAT5 and KAT7. Induces cell-cycle exit and cellular senescence, and inhibits growth of B-cell lymphoma cells in vitro (IC50 = 0.25 μM). Reduces H3K9ac in tumor cells, and decreases tumor burden and spleen weight in a mouse lymphoma model. Purity 98%. MW (observed): 389.38 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 2-Fluoro-N'-(3-fluoro-5-(pyridin-2-yl)benzoyl)benzenesulfonohydrazide |
Gene, Accession, CAS # | CAS: 2055397-28-7 |
Catalog # | 6692/10 |
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Order / More Info | WM 1119 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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