产品详情 |
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Product Name | WHI-P 154 |
Description | JAK3 inhibitor (IC50 = 1.8 μM) that displays no activity at JAK1 or JAK2. Inhibits STAT1 activation, iNOS expression and NO production in macrophages in vitro. Also inhibits other common kinases including EGFR (IC50 = 4 nM), Src, Abl, VEGFR, MAPK and PI 3-K and induces apoptosis in human glioblastoma cell lines (IC50 = 158 μM). Induces differentiation of neural progenitor cells. Purity 99%. MW (observed): 376.2 |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 2-Bromo-4-[(6,7-dimethoxy-4-quinazolinyl)amino]phenol |
Gene, Accession, CAS # | CAS: 211555-04-3 |
Catalog # | 3115/25 |
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Order / More Info | WHI-P 154 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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