产品详情 |
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Product Name | Valproic acid, sodium salt |
Description | Histone deacetylase inhibitor (IC50 = 400 μM) that exhibits anticancer, anti-inflammatory and neuroprotective effects. Displays anticonvulsive activity via an increase in GABA levels and decreases Aβ production in animal models of Alzheimer's disease. Also attenuates NMDA-mediated excitation, blocks voltage-gated Na+ channels and modulates firing of neurons. Enables induction of pluripotent stem cells from somatic cells by Oct4 and Sox2. Can induce autophagy by inhibiting inositol synthesis. MW (observed): 166.19. |
Size | 100 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Sodium 2-propylpentanoate. VPA, Sodium Valproate |
Gene, Accession, CAS # | CAS: 1069-66-5 |
Catalog # | 2815/100 |
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Order / More Info | Valproic acid, sodium salt from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 24919179, 25568126, 29396410 |
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