| 产品详情 |
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| Product Name | Pimavanserin |
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| Description | A 5-HT2A inverse agonist (IC50 = 1.86 nM; Ki = 0.5 nM); selective for 5-HT2A over a panel of 65 ion channels, enzymes, and receptors (Kis = >100 nM); reduces DOI-induced head-twitch behavior and prepulse inhibition deficits in rats at doses of 3 mg/kg, p.o. and 1-10 mg/kg, s.c., respectively; exhibits antipsychotic-like activity, reducing (+)-MK-801-induced hyperactivity in mice; acts synergistically with haloperidol or risperidone to suppress (+)-MK-801-induced hyperactivity and attenuates haloperidol- and risperidone-induced catalepsy in rats |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | nuplazid anti-psychotic 5HT 5HT-2A 5HT2A MK801 |
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| Gene, Accession, CAS # | CAS: 706779-91-1 |
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| Catalog # | 23462-10 |
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| Order / More Info | Pimavanserin from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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