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Product Name | UNC 1999 |
Description | Potent and SAM-competitive EZH2/EZH1 lysine methyltransferase inhibitor (IC50 values are 10 and 45 nM, respectively). Selective for EZH2/EZH1 over a panel of other methyltransferases and non-epigenetic targets. Reduces H3K27me3 levels in vitro. Prolongs survival of MLL-AF9 bearing mice. Orally bioavailable. Negative Control also available.. Purity 99%. MW (observed): 569.74 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | N-[(1,2-Dihydro-6-methyl-2-oxo-4-propyl-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[6-[4-(1-methylethyl)-1-piperazinyl]-3-pyridinyl]-1H-indazole-4-carboxamide |
Gene, Accession, CAS # | CAS: 1431612-23-5 |
Catalog # | 4904/50 |
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Order / More Info | UNC 1999 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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