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| Product Name | VX 745 |
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| Description | Highly potent and selective p38α inhibitor (IC50 = 10 nM). Also blocks TNFα production in LPS-stimulated HWB in vitro (IC50 = 177 nM). Displays 1000-fold selectivity over closely related kinases, including ERK1, MK2 and JNK1-3. Purity 98%. MW (observed): 436.26 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 5-(2,6-Dichlorophenyl)-2-[2,4-difluorophenyl)thio]-6H-pyrimido[1,6-b]pyridazin-6-one |
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| Gene, Accession, CAS # | CAS: 209410-46-8 |
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| Catalog # | 3915/50 |
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| Price | |
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| Order / More Info | VX 745 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 24244164 |
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| 产品资料 |
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