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Product Name | VU 0360172 hydrochloride |
Description | Positive allosteric modulator of mGlu5 receptors (EC50 = 16 nM; Ki = 195 nM). Selective for mGlu5; displays no significant activity at mGlu1, mGlu2 or mGlu4 receptors. Exhibits antipsychotic-like activity in a rodent model. Also reduces spontaneous spike and wave discharges without affecting motor behaviour in a rat model of absence epilepsy. Purity 98%. MW (observed): 330.78 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | N-Cyclobutyl-6-[2-(3-fluorophenyl)ethynyl]-3-pyridinecarboxamide hydrochloride |
Gene, Accession, CAS # | CAS: 1309976-62-2 |
Catalog # | 4323/50 |
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Order / More Info | VU 0360172 hydrochloride from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 30316834 |
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