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| Product Name | VU 29 |
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| Description | Potent allosteric potentiator at the rat mGlu5 receptor (EC50 = 9 nM); binds to the MPEP (Cat. No. 1212) allosteric site (Ki app = 244 nM). Selective for mGlu5 over mGlu1 and mGlu2 receptors (EC50 values are 557 nM and 1.51 μM for mGlu1 and mGlu2 respectively). Potentiates both DHPG-induced LTP and threshold θ-burst stimulation (TBS)-induced LTP in rat hippocampal slices. Analog of CDPPB (Cat. No. 3235). Purity 99%. MW (observed): 384.39 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-(1,3-Diphenyl-1H-pyrazolo-5-yl)-4-nitrobenzamide |
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| Gene, Accession, CAS # | CAS: 890764-36-0 |
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| Catalog # | 4458/10 |
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| Order / More Info | VU 29 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 25031220 |
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