产品详情 |
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Product Name | VU 0483605 |
Description | Positive allosteric modulator at mGlu1 (EC50 values are 356 and 390 nM for rat and human receptors, respectively). Exhibits >25-fold selectivity for mGlu1 over mGlu4. Potentiates the decreased glutamate-induced calcium response in mGlu1 mutant cell models of schizophrenia. Purity 98%. MW (observed): 446.67 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 3-Chloro-N-[3-chloro-4-(4-chloro-1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)phenyl]-2-pyridinecarboxamide |
Gene, Accession, CAS # | CAS: 1623101-11-0 |
Catalog # | 5377/50 |
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Order / More Info | VU 0483605 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 29514854 |
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