产品详情 |
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Product Name | IU1-47 |
Description | Potent USP14 inhibitor (IC50 = 60 nM). Demonstrates >30-fold selectivity for USP14 over USP5 (IsoT). Enhances degradation of proteasome substrates in vitro. Increases degradation of wild type and pathological tau in MEFs, primary neuronal cultures and human iPSC derived neurons. Purity 98%. MW (observed): 330.85 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 1-[1-(4-Chlorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-piperidinyl)ethanone |
Gene, Accession, CAS # | CAS: 670270-31-2 |
Catalog # | 6443/10 |
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Order / More Info | IU1-47 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 28972160 |
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