产品详情 |
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Product Name | ITD 1 |
Description | Selective inhibitor of TGF-β signaling (IC50 = 0.85 μM); displays little or no inhibition of activin, Wnt or BMP signaling pathways. Induces proteasomal degradation of the TGF-β type II receptor. Inhibits TGF-β-induced mesoderm formation from mouse embryonic stem cells (ESCs) during early differentiation; selectively promotes the differentiation of ESCs to cardiomyocytes in vitro between days 3-5. Does not induce differentiation of vascular smooth muscle cells or endothelial cells. Purity 98%. MW (observed): 415.52 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 4-[1,1'-Biphenyl]-4-yl-1,4,5,6,7,8-hexahydro-2,7,7-trimethyl-5-oxo-3-quinolinecarboxylic acid ethyl ester |
Gene, Accession, CAS # | CAS: 1099644-42-4 |
Catalog # | 5068/50 |
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Order / More Info | ITD 1 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 29510118 |
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