产品详情 |
Edit |   |
Product Name | Sunitinib malate |
Description | Potent, ATP-competitive VEGFR, PDGFRβ and KIT inhibitor (Ki values are 2, 9, 17, 8 and 4 nM for VEGFR -1, -2, -3, PDGFRβ and KIT respectively). Also inhibits cellular receptor phosphorylation of FLT3, RET and CSF-1R. Exhibits antiangiogenic and antitumor activity in multiple xenograft models. Purity 99%. MW (observed): 532.56 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidine)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide (2S)-2-hydroxybutanedioate salt. SU 11248 |
Gene, Accession, CAS # | CAS: 341031-54-7 |
Catalog # | 3768/50 |
Price | |
Order / More Info | Sunitinib malate from TOCRIS BIOSCIENCE
|
Product Specific References | PubMed: 24550330, 24759231, 25353068, 25943352 |
产品资料 |
|
|