产品详情 |
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Antigenic Specificity | NEIL3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NEIL3 Polyclonal Antibody. DNA glycosylase which prefers single-stranded DNA (ssDNA), or partially ssDNA structures such as bubble and fork structures, to double-stranded DNA (dsDNA). In vitro, displays strong glycosylase activity towards the hydantoin lesions spiroiminodihydantoin (Sp) and guanidinohydantoin (Gh) in both ssDNA and dsDNA; also recognizes FapyA, FapyG, 5-OHU, 5-OHC, 5-OHMH, Tg and 8-oxoA lesions in ssDNA. No activity on 8-oxoG detected. Also shows weak DNA-(apurinic or apyrimidinic site) lyase activity. In vivo, appears to be the primary enzyme involved in removing Sp and Gh from ssDNA in neonatal tissues. Seems to be an important facilitator of cell proliferation in certain populations, for example neural stem/progenitor ce |
Immunogen | n/a |
Other Names | FGP2; FLJ10858; FPG2; NEI3; hFPG2; hNEI3 |
Gene, Accession # | Entrez: 55247; Uniprot: Q8TAT5 |
Catalog # | PA5-66796 |
Price | |
Order / More Info | NEIL3 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
产品资料 |
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