| 产品详情 |
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| Product Name | NVP BSK 805 |
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| Description | Potent JAK2 inhibitor (IC50 = 0.48 nM). Exhibits >20-fold selectivity for JAK2 over TYK2, JAK3 and JAK1 (IC50 values are 10.8, 18.7 and 31.6 nM, respectively). Inhibits proliferation and induces apoptosis of JAK2V617F-bearing acute myeloid leukemia cells in vitro and in vivo. Also inhibits erythropoietin-induced polycythemia. Orally bioavailable. Purity 98%. MW (observed): 599.94 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 8-[3,5-Difluoro-4-(4-morpholinylmethyl)phenyl]-2-[1-(4-piperidinyl)-1H-pyrazol-4-yl]quinoxaline trihydrochloride |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 5818/50 |
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| Price | |
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| Order / More Info | NVP BSK 805 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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| 产品资料 |
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