产品详情 |
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Product Name | AZD 1480 |
Description | Potent and selective JAK2 inhibitor (IC50 < 3 nM). Exhibits >50-fold selectivity for JAK2 over JAK3. Exhibits antitumor effects and inhibits formation of lung metastases in a mouse renal cancer model. Also inhibits STAT3 signaling, tumor angiogenesis and myeloid cell migration in vivo. Purity 98%. MW (observed): 348.77 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 5-Chloro-N2-[(1S)-1-(5-fluoro-2-pyrimidinyl)ethyl]-N4-(5-methyl-1H-pyrazol-3-yl)-2,4-pyrimidine-2,4-diamine |
Gene, Accession, CAS # | CAS: 935666-88-9 |
Catalog # | 5617/10 |
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Order / More Info | AZD 1480 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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